TLR4 抗体
Quick Overview for TLR4 抗体 (ABIN217676)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. Has been demonstrated to block activation of monocytes with LPS.
-
纯化方法
- Protein G purified
-
内毒素水平
- Low Endotoxin
-
免疫原
- Ba/F3 cell line expressing TLR4 (CD284).
-
亚型
- IgG2a
-
-
-
-
应用备注
-
Approved: Flo (1:10 - 1:50), Func, IP, WB
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.
Not recommended for: IHC-P -
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- PBS.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
-
-
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
别名
- TLR4
-
背景
-
Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll -
基因ID
- 7099
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
-